Students Projects

Semester/master projects

Implementation of retinal tracking for in vivo imaging

Goals: Investigation and design on camera-based retinal tracking system.

Context:

We developed at LAPD a new technology for in-vivo retinal imaging in-vivo retinal imaging. The proposed project aims at implementing a retinal tracking capability in a prototype. Retinal tracking is a crucial feature for clinical instruments since it allows for follow up of patients as well as a proper image visualization during the acquisition. In the state of the art instruments based on Optical Coherence Tomography of Scanning Laser Ophthalmoscope, the tracking is implemented thanks to galvo mirrors which send the scanning beam at the desired location on the retina. In our technology, the imaging is based on a camera, without any scanning parts. Therefore, the retinal tracking needs to be designed in a different way compared to scanning instruments.
Details of the project…

Experimental measurement of light diffusion in eye tissues using transscleral illumination

Goals: Design an experimental setup for diffusion measurements, understand the light scattering in eye tissues.

Context:

We developed at LAPD a new technology for in-vivo retinal imaging. The proposed project is a joint LAPD and LIFMET (Georges Wagnières) project, which aim at understanding and measuring the light scattering in eye tissues with transscleral illumination (Fig. 1) in the near infrared window (750 nm – 1100 nm). The measurements will be performed ex-vivo on fixed and non-fixed pigs’ eyes thanks to endoscopic probe endoscopic probe.

Details of the project…

Laser-based needle-free injection in minimally invasive deviceContext:

LAPD is an exciting lab where photonics and optical engineering is translated into a real application.
One of our expertise is in optofluidics – the field where optics is combined with liquids. We have recently developed the laser-based device for needle-free injection into biological tissue. In our solution a high power laser pulse is focused via objective into the glass capillary filled with the liquid which is subsequently ejected with velocities exceeding the speed of sound. The kinetic energy of the jet is sufficient for penetration of physical barriers such as human skin, tumours or other soft tissues for
distribution of drugs of gene delivery.
Details of the project…

Image processing algorithms for volumetric 3D printing

We are developing a 3D printing method based on volumetric solidification, as opposed to the layer-by-layer processes used by most current 3D printers. This volumetric 3D printing method works by sending computed light patterns into a container of photosensitive resin as it rotates. The objective of the project is to write an algorithm that calculates optimized patterns of light so that the desired parts of the photosensitive resin become solidified as accurately as possible into the final object. The work includes modeling the light rays that enter and get absorbed in the cylindrical build volume, formulating the problem in sparse matrix form, and developing an efficient way to solve the inverse problem of finding the optimal projections that yield the desired object.

Details of the project…